A Novel Technique for Chronic Kidney Disease Prediction using Glowworm Swarm Algorithm with Adaptive Neuro Fuzzy Inference System
Abstract
The term chronic kidney disease (CKD) describes the progressive loss of kidney function; according to recent studies, the incidence of this ailment is increasing yearly. The great accuracy of machine learning approaches in diagnosing chronic kidney disease has made them more important in medical diagnosis. More recently, efforts have been made to optimize these methods by using efficient feature selection algorithms with the goal of minimizing dataset dimensionality. This research suggests using an advanced feature selection technique using Tabu Search (TS) based Stochastic Diffusion Search (SDS). 19 characteristics were chosen and 5 features were eliminated after using this method. When it comes to diagnosing CKD, the proposed Adaptive Neuro Fuzzy Inference System (ANFIS) has outperformed other state of art machine learning techniques. Through the use of an enhanced diagnostic technique utilizing the glowworm swarm optimization algorithm (GSO), this work improves the ANFIS model. By simulating glowworm behavior during food hunting, this global optimization technique increases ANFIS efficiency. Furthermore, to improve the convergence speed during network training, the suggested method incorporates a hybrid learning algorithm that combines the conjugate gradient descent and the Least Square Estimator (LSE). Fuzzy logic is added to the Adaptive Backpropagation Neural Network (ABPNN) classifier to boost performance. Findings highlight the effectiveness of the ABPNN-GSO-ANFIS in diagnosing CKD, with 99.52% accuracy, 99.34% precision, and 97.82% recall achieved.
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A Khade, Vidhate AV, “A novel approach using artificial intelligence for early prognosis of chronic kidney disease in Asian population,” Panamerican Mathematical Journal, vol. 35, no. 2s, pp. 387–407, Dec. 2024, doi: 10.52783/pmj.v35.i2s.2765.
M. Elhoseny, K. Shankar, and J. Uthayakumar, “Intelligent Diagnostic Prediction and Classification System for Chronic kidney Disease,” Scientific Reports, vol. 9, no. 1, Jul. 2019, doi: 10.1038/s41598-019-46074-2.
N. H. Cai, K. Mikolajczyk, and J. Matas, “Learning linear discriminant projections for dimensionality reduction of image descriptors,” IEEE Transactions on Pattern Analysis and Machine Intelligence, vol. 33, no. 2, pp. 338–352, Apr. 2010, doi: 10.1109/tpami.2010.89.
K. Nagawa et al., “Three-dimensional convolutional neural network-based classification of chronic kidney disease severity using kidney MRI,” Scientific Reports, vol. 14, no. 1, Jul. 2024, doi: 10.1038/s41598-024-66814-3.
Hadap, Ajani, and Khade, “A Decision Support System for Health Management: Integrating Big Data and Machine Learning in Information Systems,” Journal of Information Systems Engineering and Management, vol. 10, no. 1, pp. 13–27, Jan. 2025, doi: 10.52783/jisem.v10i1.2.
Hadap, Ajani, and Khade, “Implementation of Health Information Systems for Streamlined Patient Workflow and Management in Rural Healthcare,” Journal of Information Systems Engineering and Management, vol. 10, no. 1, Jan. 2025, doi: 10.52783/jisem.v10i1.4.
A. Khade, A. V. Vidhate, and D. Vidhate, “Design of an Optimized Self-Acclimation Graded Boolean PSO with Back Propagation Model and Cuckoo Search Heuristics for Automatic Prediction of Chronic Kidney Disease,” Journal of Mobile Multimedia, vol. 19, no. 6, 2023, doi: 10.13052/jmm1550-4646.1962.
R. Tkachenko, I. Izonin, P. Vitynskyi, N. Lotoshynska, and O. Pavlyuk, “Development of the Non-Iterative Supervised Learning Predictor based on the ITO Decomposition and SGTM Neural-Like Structure for managing medical insurance costs,” Data, vol. 3, no. 4, p. 46, Oct. 2018, doi: 10.3390/data3040046.
R. S, B. Bharathi, P. Jeyanthi, and M. Ramesh, “Chronic Kidney Disease Prediction using Machine Learning Models,” International Journal of Engineering and Advanced Technology, vol. 9, no. 1, pp. 6364–6367, Oct. 2019, doi: 10.35940/ijeat.a2213.109119.
Y. Zhang, M. Brady, and S. Smith, “Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm,” IEEE Transactions on Medical Imaging, vol. 20, no. 1, pp. 45–57, Jan. 2001, doi: 10.1109/42.906424.
N. H. Peng, N. F. Long, and C. Ding, “Feature selection based on mutual information criteria of max-dependency, max-relevance, and min-redundancy,” IEEE Transactions on Pattern Analysis and Machine Intelligence, vol. 27, no. 8, pp. 1226–1238, Jun. 2005, doi: 10.1109/tpami.2005.159.
R. M. X. Wu et al., “A comparative analysis of the principal component analysis and entropy weight methods to establish the indexing measurement,” PLoS ONE, vol. 17, no. 1, p. e0262261, Jan. 2022, doi: 10.1371/journal.pone.0262261.
X. Feng, S. Li, C. Yuan, P. Zeng, and Y. Sun, “Prediction of Slope Stability using Naive Bayes Classifier,” KSCE Journal of Civil Engineering, vol. 22, no. 3, pp. 941–950, Mar. 2018, doi: 10.1007/s12205-018-1337-3.
M. A. Hearst, S. T. Dumais, E. Osuna, J. Platt, and B. Scholkopf, “Support vector machines,” IEEE Intelligent Systems and Their Applications, vol. 13, no. 4, pp. 18–28, Jul. 1998, doi: 10.1109/5254.708428.
E. Dritsas and M. Trigka, “Stroke Risk Prediction with Machine Learning Techniques,” Sensors, vol. 22, no. 13, p. 4670, Jun. 2022, doi: 10.3390/s22134670.
D. Zhang and Y. Gong, “The comparison of LightGBM and XGBOOST Coupling factor analysis and prediagnosis of acute liver failure,” IEEE Access, vol. 8, pp. 220990–221003, Jan. 2020, doi: 10.1109/access.2020.3042848.
N. Fazakis, O. Kocsis, E. Dritsas, S. Alexiou, N. Fakotakis, and K. Moustakas, “Machine Learning Tools for Long-Term Type 2 Diabetes Risk Prediction,” IEEE Access, vol. 9, pp. 103737–103757, Jan. 2021, doi: 10.1109/access.2021.3098691.
E. Dritsas, N. Fazakis, O. Kocsis, N. Fakotakis, and K. Moustakas, “Long-Term Hypertension Risk Prediction with ML Techniques in ELSA Database,” Lecture notes in computer science, 2021, pp. 113–120, doi: 10.1007/978-3-030-92121-7_9.
P. Ponikowski et al., “2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure,” European Heart Journal, vol. 37, no. 27, pp. 2129–2200, May 2016, doi: 10.1093/eurheartj/ehw128.
R. D. Cebul, T. E. Love, A. K. Jain, and C. J. Hebert, “Electronic health records and quality of diabetes care,” New England Journal of Medicine, vol. 365, no. 9, pp. 825–833, Sep. 2011, doi: 10.1056/nejmsa1102519.
Y. Zhu, D. Bi, M. Saunders, and Y. Ji, “Prediction of chronic kidney disease progression using recurrent neural network and electronic health records,” Scientific Reports, vol. 13, no. 1, Dec. 2023, doi: 10.1038/s41598-023-49271-2.
K. W. Kaye and M. E. Goldberg, “Applied anatomy of the kidney and ureter,” Urologic Clinics of North America, vol. 9, no. 1, pp. 3–13, Feb. 1982, doi: 10.1016/s0094-0143(21)00709-6.
A. S. Go, G. M. Chertow, D. Fan, C. E. McCulloch, and C.-Y. Hsu, “Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization,” New England Journal of Medicine, vol. 351, no. 13, pp. 1296–1305, Sep. 2004, doi: 10.1056/nejmoa041031.
F. Zhou et al., “Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study,” The Lancet, vol. 395, no. 10229, pp. 1054–1062, Mar. 2020, doi: 10.1016/s0140-6736(20)30566-3.
H. Li, W. Lu, A. Wang, H. Jiang, and J. Lyu, “Changing epidemiology of chronic kidney disease as a result of type 2 diabetes mellitus from 1990 to 2017: Estimates from Global Burden of Disease 2017,” Journal of Diabetes Investigation, vol. 12, no. 3, pp. 346–356, Jul. 2020, doi: 10.1111/jdi.13355.
B. R. Lane et al., “Factors predicting renal functional outcome after partial nephrectomy,” The Journal of Urology, vol. 180, no. 6, pp. 2363–2369, Dec. 2008, doi: 10.1016/j.juro.2008.08.036.
D. W. Crabb, G. Y. Im, G. Szabo, J. L. Mellinger, and M. R. Lucey, “Diagnosis and Treatment of Alcohol‐Associated Liver Diseases: 2019 Practice Guidance from the American Association for the Study of Liver Diseases,” Hepatology, vol. 71, no. 1, pp. 306–333, Jul. 2019, doi: 10.1002/hep.30866.
N. Thakur and C. Y. Han, “A study of fall Detection in Assisted Living: Identifying and Improving the optimal Machine Learning Method,” Journal of Sensor and Actuator Networks, vol. 10, no. 3, p. 39, Jun. 2021, doi: 10.3390/jsan10030039.
P. Dixon et al., “Cost-effectiveness of telehealth for patients with depression: evidence from the Healthlines randomised controlled trial,” BJPsych Open, vol. 2, no. 4, pp. 262–269, Jul. 2016, doi: 10.1192/bjpo.bp.116.002907.
W. G. Herrington et al., “Empagliflozin in Patients with Chronic Kidney Disease,” New England Journal of Medicine, vol. 388, no. 2, pp. 117–127, Nov. 2022, doi: 10.1056/nejmoa2204233.
E. Gürbüz and E. Kılıç, “A new adaptive support vector machine for diagnosis of diseases,” Expert Systems, vol. 31, no. 5, pp. 389–397, Aug. 2013, doi: 10.1111/exsy.12051.
J. Parab, M. Sequeira, M. Lanjewar, C. Pinto, and G. Naik, “Backpropagation Neural Network-Based machine learning model for prediction of blood urea and glucose in CKD patients,” IEEE Journal of Translational Engineering in Health and Medicine, vol. 9, pp. 1–8, Jan. 2021, doi: 10.1109/jtehm.2021.3079714.
K. J. Foreman et al., “Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories,” The Lancet, vol. 392, no. 10159, pp. 2052–2090, Oct. 2018, doi: 10.1016/s0140-6736(18)31694-5.
K. Nagawa et al., “Three-dimensional convolutional neural network-based classification of chronic kidney disease severity using kidney MRI,” Scientific Reports, vol. 14, no. 1, Jul. 2024, doi: 10.1038/s41598-024-66814-3.
P. Sidhu et al., “The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2017 (Long Version),” Ultraschall in Der Medizin - European Journal of Ultrasound, vol. 39, no. 02, pp. e2–e44, Mar. 2018, doi: 10.1055/a-0586-1107.
I. A. Pasadana et al., “Chronic kidney disease prediction by using different decision tree techniques,” Journal of Physics Conference Series, vol. 1255, no. 1, p. 012024, Aug. 2019, doi: 10.1088/1742-6596/1255/1/012024.
A. Khade, A. V. Vidhate, and D. Vidhate, “FFN-XGB- design of a hybrid feed forward neural network and extreme gradient boosting model for early prediction of chronic kidney disease,” International Journal of Systems Assurance Engineering and Management, Jun. 2023, doi: 10.1007/s13198-023-01993-2.
Y. Ganin et al., “Domain-Adversarial training of neural networks,” Advances in computer vision and pattern recognition, 2017, pp. 189–209. doi: 10.1007/978-3-319-58347-1_10.
P. Chittora et al., “Prediction of Chronic kidney Disease - a Machine learning perspective,” IEEE Access, vol. 9, pp. 17312–17334, Jan. 2021, doi: 10.1109/access.2021.3053763.
D. Bhattacharya, S. Banerjee, S. Bhattacharya, B. U. Shankar, and S. Mitra, “GAN-Based Novel Approach for Data Augmentation with Improved Disease Classification,” Algorithms for intelligent systems, 2019, pp. 229–239. doi: 10.1007/978-981-15-1100-4_11.
S. Maldonado, J. López, and C. Vairetti, “An alternative SMOTE oversampling strategy for high-dimensional datasets,” Applied Soft Computing, vol. 76, pp. 380–389, Dec. 2018, doi: 10.1016/j.asoc.2018.12.024.
X. Shi, Y. D. Wong, C. Chai, and M. Z.-F. Li, “An Automated Machine Learning (AutoML) method of risk Prediction for Decision-Making of Autonomous vehicles,” IEEE Transactions on Intelligent Transportation Systems, vol. 22, no. 11, pp. 7145–7154, Jul. 2020, doi: 10.1109/tits.2020.3002419.
S. Nusinovici et al., “Logistic regression was as good as machine learning for predicting major chronic diseases,” Journal of Clinical Epidemiology, vol. 122, pp. 56–69, Mar. 2020, doi: 10.1016/j.jclinepi.2020.03.002.
V. K. Yarasuri, G. K. Indukuri, and A. K. Nair, “Prediction of hepatitis disease using machine learning technique,” 2019 Third International Conference on I-SMAC (IoT in Social, Mobile, Analytics and Cloud) (I-SMAC), Dec. 2019, doi: 10.1109/i-smac47947.2019.9032585.
K. G. M. Moons et al., “PROBAST: a tool to assess risk of bias and applicability of prediction model Studies: Explanation and Elaboration,” Annals of Internal Medicine, vol. 170, no. 1, p. W1, Dec. 2018, doi: 10.7326/m18-1377.
B. Waschneck et al., “Optimization of global production scheduling with deep reinforcement learning,” Procedia CIRP, vol. 72, pp. 1264–1269, Jan. 2018, doi: 10.1016/j.procir.2018.03.212.
E.-H. A. Rady and A. S. Anwar, “Prediction of kidney disease stages using data mining algorithms,” Informatics in Medicine Unlocked, vol. 15, p. 100178, Jan. 2019, doi: 10.1016/j.imu.2019.100178.
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